English
knottin
From knot + -in.
Formed from knot + -in
Proto-Germanic *knuttô ‘a knot’
Proto-West Germanic *knottō
Old English cnotta
Middle English knotte ‘knot, tie’
English knot
Today it means
noun Inhibitor cystine knot
Language periods are conventional ranges, not dates for this word.
Etymograph / knottin