English
macrocycle
From macro- + cycle.
Proto-Indo-European *meh₂ḱ- ‘to increase’
Proto-Indo-European *mh₂ḱrós ‘lean, meager’
Proto-Hellenic *makrós
Ancient Greek μακρός ‘long’
English macro-
Proto-Indo-European *kʷel- ‘to turn’
…
Proto-Hellenic *kúklos ‘circle, wheel’
Ancient Greek κύκλος ‘circle, ring’
Late Latin cyclus
Middle English cicle ‘fixed length period of years’
English cycle
Today it means
noun a cyclic macromolecule, or a macrocyclic portion of a molecule
Language periods are conventional ranges, not dates for this word.
Etymograph / macrocycle